Joseph Baur is a Professor in the Department of Physiology and the Institute for Diabetes, Obesity, and Metabolism at the Perelman School of Medicine of the University of Pennsylvania.

He has made key contributions to the understanding of how metabolism and dietary factors influence longevity. His laboratory at Penn is currently focused on the use of small molecules to understand and mimic the health-promoting effects of caloric restriction in rodents. Within this area, a central focus of the lab is on understanding how changes in nicotinamide adenine dinucleotide (NAD+) metabolism contribute to aging, obesity, and disease.